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Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis

OBJECTIVES: Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug efficacy. Little is known about the genes or genetic variants contributing to the risk of developing these toxicities or chemotherapeutic response. Thus, we have applied a cel...

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Main Authors: Shukla, Sunita J., Duan, Shiwei, Badner, Judith A., Wu, Xiaolin, Dolan, M. Eileen
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567113/
https://ncbi.nlm.nih.gov/pubmed/18300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f5e605
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