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Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis

OBJECTIVES: Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug efficacy. Little is known about the genes or genetic variants contributing to the risk of developing these toxicities or chemotherapeutic response. Thus, we have applied a cel...

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Autors principals: Shukla, Sunita J., Duan, Shiwei, Badner, Judith A., Wu, Xiaolin, Dolan, M. Eileen
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567113/
https://ncbi.nlm.nih.gov/pubmed/18300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f5e605
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