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Identification of genomic regions contributing to etoposide-induced cytotoxicity

Etoposide is routinely used in combination based chemotherapy for testicular cancer and small-cell lung cancer; however, myelosuppression, therapy-related leukemia and neurotoxicity limit its utility. To determine the genetic contribution to cellular sensitivity to etoposide, we evaluated cell growt...

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Bibliografiske detaljer
Main Authors: Bleibel, Wasim K., Duan, Shiwei, Huang, R. Stephanie, Kistner, Emily O., Shukla, Sunita J., Wu, Xiaolin, Badner, Judith A., Dolan, M. Eileen
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714550/
https://ncbi.nlm.nih.gov/pubmed/19089452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0607-4
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