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Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis

OBJECTIVES: Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug efficacy. Little is known about the genes or genetic variants contributing to the risk of developing these toxicities or chemotherapeutic response. Thus, we have applied a cel...

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Detalhes bibliográficos
Main Authors: Shukla, Sunita J., Duan, Shiwei, Badner, Judith A., Wu, Xiaolin, Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567113/
https://ncbi.nlm.nih.gov/pubmed/18300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f5e605
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