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Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis

OBJECTIVES: Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug efficacy. Little is known about the genes or genetic variants contributing to the risk of developing these toxicities or chemotherapeutic response. Thus, we have applied a cel...

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Bibliografiske detaljer
Main Authors: Shukla, Sunita J., Duan, Shiwei, Badner, Judith A., Wu, Xiaolin, Dolan, M. Eileen
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567113/
https://ncbi.nlm.nih.gov/pubmed/18300947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f5e605
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