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Identification of Genetic Variants Contributing to Cisplatin-Induced Cytotoxicity by Use of a Genomewide Approach

Cisplatin, a platinating agent commonly used to treat several cancers, is associated with nephrotoxicity, neurotoxicity, and ototoxicity, which has hindered its utility. To gain a better understanding of the genetic variants associated with cisplatin-induced toxicity, we present a stepwise approach...

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Autori principali: Huang, R. Stephanie , Duan, Shiwei , Shukla, Sunita J. , Kistner, Emily O. , Clark, Tyson A. , Chen, Tina X. , Schweitzer, Anthony C. , Blume, John E. , Dolan, M. Eileen 
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Human Genetics 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950832/
https://ncbi.nlm.nih.gov/pubmed/17701890
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