Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor

While negative effect of smoking on the resistance to viral infections was known, the underlying mechanisms remained unclear. Here we report that products of cigarette smoking compromise the cellular anti-viral defenses by inhibiting the signaling induced by Type I interferon (IFN). Cigarette smokin...

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Detaylı Bibliyografya
Asıl Yazarlar: HuangFu, Wei-Chun, Liu, Jianghuai, Harty, Ronald N., Fuchs, Serge Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567056/
https://ncbi.nlm.nih.gov/pubmed/18722370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.08.013
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