Inflammatory signaling compromises cell responses to interferon alpha

Interferon alpha (IFNα) is widely used for treatment of melanoma and certain other malignancies. This cytokine as well as the related IFNβ exerts potent anti-tumorigenic effects; however, their efficacy in patients is often suboptimal. Here we report that inflammatory signaling impedes the effects o...

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Main Authors: HuangFu, Wei-Chun, Qian, Juan, Liu, Chengbao, Liu, Jianghuai, Lokshin, Anna E., Baker, Darren P., Rui, Hallgeir, Fuchs, Serge Y
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175348/
https://ncbi.nlm.nih.gov/pubmed/21666722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.221
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