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Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2

Alpha interferon (IFN-α) controls homeostasis of hematopoietic stem cells, regulates antiviral resistance, inhibits angiogenesis, and suppresses tumor growth. This cytokine is often used to treat cancers and chronic viral infections. The extent of cellular responses to IFN-α is limited by the IFN-in...

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Detalhes bibliográficos
Main Authors: Zheng, Hui, Qian, Juan, Varghese, Bentley, Baker, Darren P., Fuchs, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028644/
https://ncbi.nlm.nih.gov/pubmed/21173164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01154-10
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