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Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2
Alpha interferon (IFN-α) controls homeostasis of hematopoietic stem cells, regulates antiviral resistance, inhibits angiogenesis, and suppresses tumor growth. This cytokine is often used to treat cancers and chronic viral infections. The extent of cellular responses to IFN-α is limited by the IFN-in...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028644/ https://ncbi.nlm.nih.gov/pubmed/21173164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01154-10 |
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