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Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor

While negative effect of smoking on the resistance to viral infections was known, the underlying mechanisms remained unclear. Here we report that products of cigarette smoking compromise the cellular anti-viral defenses by inhibiting the signaling induced by Type I interferon (IFN). Cigarette smokin...

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Bibliografische gegevens
Hoofdauteurs: HuangFu, Wei-Chun, Liu, Jianghuai, Harty, Ronald N., Fuchs, Serge Y.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567056/
https://ncbi.nlm.nih.gov/pubmed/18722370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.08.013
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