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The whole alignment and nothing but the alignment: the problem of spurious alignment flanks

Pairwise sequence alignment is a ubiquitous tool for inferring the evolution and function of DNA, RNA and protein sequences. It is therefore essential to identify alignments arising by chance alone, i.e. spurious alignments. On one hand, if an entire alignment is spurious, statistical techniques for...

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Hlavní autoři: Frith, Martin C., Park, Yonil, Sheetlin, Sergey L., Spouge, John L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566872/
https://ncbi.nlm.nih.gov/pubmed/18796526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn579
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