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The Gumbel pre-factor k for gapped local alignment can be estimated from simulations of global alignment
The optimal gapped local alignment score of two random sequences follows a Gumbel distribution. The Gumbel distribution has two parameters, the scale parameter λ and the pre-factor k. Presently, the basic local alignment search tool (BLAST) programs (BLASTP (BLAST for proteins), PSI-BLAST, etc.) use...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1199557/ https://ncbi.nlm.nih.gov/pubmed/16147981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki800 |
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