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New finite-size correction for local alignment score distributions

BACKGROUND: Local alignment programs often calculate the probability that a match occurred by chance. The calculation of this probability may require a “finite-size” correction to the lengths of the sequences, as an alignment that starts near the end of either sequence may run out of sequence before...

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Detalhes bibliográficos
Main Authors: Park, Yonil, Sheetlin, Sergey, Ma, Ning, Madden, Thomas L, Spouge, John L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483159/
https://ncbi.nlm.nih.gov/pubmed/22691307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-286
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