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Frameshift alignment: statistics and post-genomic applications

Motivation: The alignment of DNA sequences to proteins, allowing for frameshifts, is a classic method in sequence analysis. It can help identify pseudogenes (which accumulate mutations), analyze raw DNA and RNA sequence data (which may have frameshift sequencing errors), investigate ribosomal frames...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Sheetlin, Sergey L., Park, Yonil, Frith, Martin C., Spouge, John L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253828/
https://ncbi.nlm.nih.gov/pubmed/25172925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu576
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