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Role of the N-Terminal Domain of φC31 Integrase in attB-attP Synapsis

φC31 integrase is a serine recombinase containing an N-terminal domain (NTD) that provides catalytic activity and a large C-terminal domain that controls which pair of DNA substrates is able to synapse. We show here that substitutions in amino acid V129 in the NTD can lead to defects in synapsis and...

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書誌詳細
主要な著者: Rowley, Paul A., Smith, Margaret C. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566186/
https://ncbi.nlm.nih.gov/pubmed/18689475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00612-08
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