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DNA binding and synapsis by the large C-terminal domain of ϕC31 integrase

The integrase (Int) from phage ϕC31 acts on the phage and host-attachment sites, attP and attB, to form an integrated prophage flanked by attL and attR. Excision (attL × attR recombination) is prevented, in the absence of accessory factors, by a putative coiled-coil motif in the C-terminal domain (C...

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Библиографические подробности
Главные авторы: McEwan, Andrew R., Rowley, Paul A., Smith, Margaret C. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724291/
https://ncbi.nlm.nih.gov/pubmed/19515935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp485
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