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A motif in the C-terminal domain of ϕC31 integrase controls the directionality of recombination
Bacteriophage ϕC31 encodes an integrase, which acts on the phage and host attachment sites, attP and attB, to form an integrated prophage flanked by attL and attR. In the absence of accessory factors, ϕC31 integrase cannot catalyse attL x attR recombination to excise the prophage. To understand the...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475636/ https://ncbi.nlm.nih.gov/pubmed/18502775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn269 |
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