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A motif in the C-terminal domain of ϕC31 integrase controls the directionality of recombination

Bacteriophage ϕC31 encodes an integrase, which acts on the phage and host attachment sites, attP and attB, to form an integrated prophage flanked by attL and attR. In the absence of accessory factors, ϕC31 integrase cannot catalyse attL x attR recombination to excise the prophage. To understand the...

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Bibliografski detalji
Glavni autori: Rowley, Paul A., Smith, Matthew C. A., Younger, Ellen, Smith, Margaret C. M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475636/
https://ncbi.nlm.nih.gov/pubmed/18502775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn269
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