Llwytho...

Engineered Mononuclear Variants in Bacillus cereus Metallo-β-lactamase BcII Are Inactive

Metallo-β-lactamases (MβLs) are zinc enzymes able to hydrolyze almost all β-lactam antibiotics, rendering them inactive, at the same time endowing bacteria high levels of resistance. The design of inhibitors active against all classes of MβLs has been hampered by their structural diversity and by th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abriata, Luciano A., González, Lisandro J., Llarrull, Leticia I., Tomatis, Pablo E., Myers, William K., Costello, Alison L., Tierney, David L., Vila, Alejandro J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565585/
https://ncbi.nlm.nih.gov/pubmed/18652482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8006912
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