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Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase ι

Human DNA polymerase ι (Polι) is one of the Y-family DNA polymerases involved in translesion synthesis (TLS), which allows continued replication at damaged DNA templates. Polι has a noncanonical PCNA-interacting protein box (PIP-box) within an internal region of the protein. Polι activity is stimula...

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Bibliographische Detailangaben
Hauptverfasser: Hishiki, Asami, Shimizu, Toshiyuki, Hanafusa, Tomo, Ohmori, Haruo, Sato, Mamoru, Hashimoto, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564886/
https://ncbi.nlm.nih.gov/pubmed/18931444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108028522
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