Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

The composition of skeletal muscle, in terms of the relative number of slow- and fast-twitch fibers, is tightly regulated to enable an organism to respond and adapt to changing physical demands. The phosphatase calcineurin and its downstream targets, transcription factors of the nuclear factor of ac...

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Détails bibliographiques
Auteurs principaux: Frey, Norbert, Frank, Derk, Lippl, Stefanie, Kuhn, Christian, Kögler, Harald, Barrientos, Tomasa, Rohr, Claudia, Will, Rainer, Müller, Oliver J., Weiler, Hartmut, Bassel-Duby, Rhonda, Katus, Hugo A., Olson, Eric N.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564612/
https://ncbi.nlm.nih.gov/pubmed/18846255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36277
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