Calsarcin-2 deficiency increases exercise capacity in mice through calcineurin/NFAT activation

The composition of skeletal muscle, in terms of the relative number of slow- and fast-twitch fibers, is tightly regulated to enable an organism to respond and adapt to changing physical demands. The phosphatase calcineurin and its downstream targets, transcription factors of the nuclear factor of ac...

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Detalhes bibliográficos
Main Authors: Frey, Norbert, Frank, Derk, Lippl, Stefanie, Kuhn, Christian, Kögler, Harald, Barrientos, Tomasa, Rohr, Claudia, Will, Rainer, Müller, Oliver J., Weiler, Hartmut, Bassel-Duby, Rhonda, Katus, Hugo A., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564612/
https://ncbi.nlm.nih.gov/pubmed/18846255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36277
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