DYRK1A Is a Novel Negative Regulator of Cardiomyocyte Hypertrophy

Activation of the phosphatase calcineurin and its downstream targets, transcription factors of the NFAT family, results in cardiomyocyte hypertrophy. Recently, it has been shown that the dual specificity tyrosine (Y) phosphorylation-regulated kinase 1A (DYRK1A) is able to antagonize calcineurin sign...

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Detalhes bibliográficos
Main Authors: Kuhn, Christian, Frank, Derk, Will, Rainer, Jaschinski, Christoph, Frauen, Robert, Katus, Hugo A., Frey, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719367/
https://ncbi.nlm.nih.gov/pubmed/19372220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006759
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