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Short Stereoselective Synthesis of α-Substituted γ-Lactams
A concise, stereoselective synthesis of α-substituted γ-lactams is reported. γ-Lactam scaffolds 2 and 3 possessing an Evans' chiral auxiliary and two types of N-substituents were successfully alkylated with different electrophiles to give α-substituted γ-lactams with reasonable diastereoselecti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562328/ https://ncbi.nlm.nih.gov/pubmed/16497007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052212q |
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