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Stereoselective Synthesis of γ-Lactams from Imines and Cyanosuccinic Anhydrides
[Image: see text] A reaction between imines and anhydrides has been developed with chiral disubstituted anhydrides and chiral imines. The synthesis of highly substituted γ-lactams with three stereogenic centers, including one quaternary center, proceeds at room temperature in high yield and with hig...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874237/ https://ncbi.nlm.nih.gov/pubmed/24070117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402554n |
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