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Stereoselective Synthesis of γ-Lactams from Imines and Cyanosuccinic Anhydrides

[Image: see text] A reaction between imines and anhydrides has been developed with chiral disubstituted anhydrides and chiral imines. The synthesis of highly substituted γ-lactams with three stereogenic centers, including one quaternary center, proceeds at room temperature in high yield and with hig...

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Autores principales: Tan, Darlene Q., Younai, Ashkaan, Pattawong, Ommidala, Fettinger, James C., Cheong, Paul Ha-Yeon, Shaw, Jared T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874237/
https://ncbi.nlm.nih.gov/pubmed/24070117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol402554n
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