Runx2 Regulates G Protein-coupled Signaling Pathways to Control Growth of Osteoblast Progenitors

Runt-related transcription factor 2 (Runx2) controls lineage commitment, proliferation, and anabolic functions of osteoblasts as the subnuclear effector of multiple signaling axes (e.g. transforming growth factor-β/BMP-SMAD, SRC/YES-YAP, and GROUCHO/TLE). Runx2 levels oscillate during the osteoblast...

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Hauptverfasser: Teplyuk, Nadiya M., Galindo, Mario, Teplyuk, Viktor I., Pratap, Jitesh, Young, Daniel W., Lapointe, David, Javed, Amjad, Stein, Janet L., Lian, Jane B., Stein, Gary S., van Wijnen, Andre J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Molecular Basis of Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562077/
https://ncbi.nlm.nih.gov/pubmed/18625716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802453200
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