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The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G(1)-related Antiproliferative Function in Osteoblasts

The Runx2 (CBFA1/AML3/PEBP2αA) transcription factor promotes skeletal cell differentiation, but it also has a novel cell growth regulatory activity in osteoblasts. We addressed here whether Runx2 activity is functionally linked to cell cycle-related mechanisms that control normal osteoblast prolifer...

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Detalhes bibliográficos
Main Authors: Galindo, Mario, Pratap, Jitesh, Young, Daniel W., Hovhannisyan, Hayk, Im, Hee-Jeong, Choi, Je-Yong, Lian, Jane B., Stein, Janet L., Stein, Gary S., van Wijnen, Andre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895256/
https://ncbi.nlm.nih.gov/pubmed/15781466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413665200
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