Protein Tyrosine Nitration of the Flavin Subunit Is Associated with Oxidative Modification of Mitochondrial Complex II in the Post-ischemic Myocardium

Increased [Formula: see text] and NO production is a key mechanism of mitochondrial dysfunction in myocardial ischemia/reperfusion injury. A crucial segment of the mitochondrial electron transport chain is succinate ubiquinone reductase (SQR or Complex II). In SQR, oxidative impairment and deglutath...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Chwen-Lih, Chen, Jingfeng, Rawale, Sharad, Varadharaj, Saradhadevi, Kaumaya, Pravin P. T., Zweier, Jay L., Chen, Yeong-Renn
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Metabolism and Bioenergetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562076/
https://ncbi.nlm.nih.gov/pubmed/18682392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802691200
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