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Peptide-based Antibodies against Glutathione-binding Domains Suppress Superoxide Production Mediated by Mitochondrial Complex I
Complex I (NQR) is a critical site of superoxide ([Image: see text]) production and the major host of redox protein thiols in mitochondria. In response to oxidative stress, NQR-derived protein thiols at the 51- and 75-kDa subunits are known to be reversibly S-glutathionylated. Although several gluta...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823436/ https://ncbi.nlm.nih.gov/pubmed/19940158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056846 |
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