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Dynamic Properties of a Type II Cadherin Adhesive Domain: Implications for the Mechanism of Strand-Swapping of Classical Cadherins
Cadherin-mediated cell adhesion is achieved through dimerization of cadherin N-terminal extracellular (EC1) domains presented from apposed cells. The dimer state is formed by exchange of N-terminal β-strands and insertion of conserved tryptophan indole side chains from one monomer into hydrophobic a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2561228/ https://ncbi.nlm.nih.gov/pubmed/18682221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.05.009 |
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