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Two-step adhesive binding by classical cadherins
Crystal structures of classical cadherins have revealed two dimeric configurations: in the first, N-terminal β-strands of EC1 domains “swap” between partner molecules. The second configuration (the “X-dimer”), also observed for T-cadherin, is mediated by residues near the EC1-2 calcium binding sites...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872554/ https://ncbi.nlm.nih.gov/pubmed/20190754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1784 |
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