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T-cadherin structures reveal a novel adhesive binding mechanism
Vertebrate genomes encode nineteen “classical” cadherins and about a hundred non-classical cadherins. Adhesion by classical cadherins depends on binding interactions in their amino terminal EC1 domains, which swap N-terminal β-strands between partner molecules from apposing cells. However, strand sw...
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| Главные авторы: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873897/ https://ncbi.nlm.nih.gov/pubmed/20190755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1781 |
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