T-cadherin structures reveal a novel adhesive binding mechanism

Vertebrate genomes encode nineteen “classical” cadherins and about a hundred non-classical cadherins. Adhesion by classical cadherins depends on binding interactions in their amino terminal EC1 domains, which swap N-terminal β-strands between partner molecules from apposing cells. However, strand sw...

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Main Authors: Ciatto, Carlo, Bahna, Fabiana, Zampieri, Niccoló, VanSteenhouse, Harper C., Katsamba, Phini, Ahlsen, Goran, Harrison, Oliver, Brasch, Julia, Jin, Xiangshu, Posy, Shoshana, Vendome, Jeremie, Ranscht, Barbara, Jessell, Thomas M., Honig, Barry, Shapiro, Lawrence
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873897/
https://ncbi.nlm.nih.gov/pubmed/20190755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1781
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