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Sequence and structural determinants of strand swapping in cadherin domains: Do all cadherins bind through the same adhesive interface?
Cadherins are cell surface adhesion proteins important for tissue development and integrity. Type I and type II, or “classical”, cadherins form adhesive dimers via an interface formed through the exchange, or “swapping”, of the N-terminal β-strands from their membrane-distal EC1 domains. Here we ask...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435303/ https://ncbi.nlm.nih.gov/pubmed/18395225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.063 |
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