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Chemically attenuated Plasmodium sporozoites induce specific immune responses, sterile immunity, and cross-protection against heterologous challenge
Vaccination with Plasmodium sporozoites attenuated by irradiation or genetic manipulation induces a protective immune response in rodent malaria models. Recently, vaccination with chemically attenuated P. berghei sporozoites (CAS) has also been shown to elicit sterile immunity in mice. Here we show...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2560175/ https://ncbi.nlm.nih.gov/pubmed/18672017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.017 |
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