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Seizure Termination by Acidosis Depends on ASIC1a
Most seizures stop spontaneously. However, the molecular mechanisms remain unknown. Earlier observations that seizures reduce brain pH and that acidosis inhibits seizures indicated that acidosis halts epileptic activity. Because acid–sensing ion channel–1a (ASIC1a) shows exquisite sensitivity to ext...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553357/ https://ncbi.nlm.nih.gov/pubmed/18536711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2132 |
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