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Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

Acid-sensing ion channel (ASIC) subunits associate to form homomeric or heteromeric proton-gated ion channels in neurons throughout the nervous system. The ASIC1a subunit plays an important role in establishing the kinetics of proton-gated currents in the CNS, and activation of ASIC1a homomeric chan...

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書誌詳細
主要な著者: Sherwood, Thomas W., Lee, Kirsten G., Gormley, Matthew G., Askwith, Candice C.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160670/
https://ncbi.nlm.nih.gov/pubmed/21715637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1665-11.2011
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