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Dynorphin Opioid Peptides Enhance Acid-Sensing Ion Channel 1a Activity and Acidosis-Induced Neuronal Death
Acid-sensing ion channel 1a (ASIC1a) promotes neuronal damage during pathological acidosis. ASIC1a undergoes a process called steady-state desensitization in which incremental pH reductions desensitize the channel and prevent activation when the threshold for acid-dependent activation is reached. We...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802056/ https://ncbi.nlm.nih.gov/pubmed/19906984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2186-09.2009 |
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