Acid-sensing ion channels in acidosis-induced injury of human brain neurons

Acidosis is a common feature of the human brain during ischemic stroke and is known to cause neuronal injury. However, the mechanism underlying acidosis-mediated injury of the human brain remains elusive. We show that a decrease in the extracellular pH evoked inward currents characteristic of acid-s...

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Библиографические подробности
Главные авторы: Li, Minghua, Inoue, Koichi, Branigan, Deborah, Kratzer, Eric, Hansen, Jillian C, Chen, Jeff W, Simon, Roger P, Xiong, Zhi-Gang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2010
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916164/
https://ncbi.nlm.nih.gov/pubmed/20216553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.30
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