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Activation of Acid-sensing Ion Channel 1a (ASIC1a) by Surface Trafficking

Acid-sensing ion channels (ASICs) are voltage-independent Na(+) channels activated by extracellular protons. ASIC1a is expressed in neurons in mammalian brain and is implicated in long term potentiation of synaptic transmission that contributes to learning and memory. In ischemic brain injury, howev...

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Detalhes bibliográficos
Main Authors: Chai, Sunghee, Li, Minghua, Branigan, Deborah, Xiong, Zhi-Gang, Simon, Roger P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857104/
https://ncbi.nlm.nih.gov/pubmed/20185828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086041
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