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Activation of Acid-sensing Ion Channel 1a (ASIC1a) by Surface Trafficking
Acid-sensing ion channels (ASICs) are voltage-independent Na(+) channels activated by extracellular protons. ASIC1a is expressed in neurons in mammalian brain and is implicated in long term potentiation of synaptic transmission that contributes to learning and memory. In ischemic brain injury, howev...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857104/ https://ncbi.nlm.nih.gov/pubmed/20185828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086041 |
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