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Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway

Oxidative stress is intimately tied to neurodegenerative diseases, including Parkinson’s disease and amyotrophic lateral sclerosis, and acute injuries, such as ischemic stroke and traumatic brain injury. Acid sensing ion channel 1a (ASIC1a), a proton-gated ion channel, has been shown to be involved...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Wu, Bao-ming, Bargaineer, Jaree, Zhang, Ling, Yang, Tao, Xiong, Zhi-gang, Leng, Tian-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285496/
https://ncbi.nlm.nih.gov/pubmed/33184449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00559-3
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