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Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway

Oxidative stress is intimately tied to neurodegenerative diseases, including Parkinson’s disease and amyotrophic lateral sclerosis, and acute injuries, such as ischemic stroke and traumatic brain injury. Acid sensing ion channel 1a (ASIC1a), a proton-gated ion channel, has been shown to be involved...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Wu, Bao-ming, Bargaineer, Jaree, Zhang, Ling, Yang, Tao, Xiong, Zhi-gang, Leng, Tian-dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285496/
https://ncbi.nlm.nih.gov/pubmed/33184449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00559-3
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