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Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a

Acid-sensing ion channel (ASIC) 1a subunit is expressed in synapses of central neurons where it contributes to synaptic plasticity. However, whether these channels can conduct Ca(2+) and thereby raise the cytosolic Ca(2+) concentration, [Ca(2+)](c), and possibly alter neuronal physiology has been un...

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Detalhes bibliográficos
Main Authors: Yermolaieva, Olena, Leonard, A. Soren, Schnizler, Mikael K., Abboud, Francois M., Welsh, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404117/
https://ncbi.nlm.nih.gov/pubmed/15082829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308636100
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