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Acid Sensing Ion Channels Regulate Neuronal Excitability by Inhibiting BK Potassium Channels

Acid sensing ion channels (ASICs) and Ca(2+) and voltage- activated potassium channels (BK) are widely present throughout the central nervous system. Previous studies have shown that when expressed together in heterologous cells, ASICs inhibit BK channels, and this inhibition is relieved by acidic e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petroff, Elena, Snitsarev, Vladislav, Gong, Huiyu, Abboud, Francois M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488431/
https://ncbi.nlm.nih.gov/pubmed/22960074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.08.114
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