Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons

BACKGROUND: Acid-sensing ion channels (ASICs) are cation channels which were activated by extracellular acidosis and involved in various physiological and pathological processes in the nervous system. Inflammasome is a key component of the innate immune response in host against harmful and irritable...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Wang, Yu-Chan, Li, Wei-Zu, Wu, Yu, Yin, Yan-Yan, Dong, Liu-Yi, Chen, Zhi-Wu, Wu, Wen-Ning
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696203/
https://ncbi.nlm.nih.gov/pubmed/26715049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0465-7
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