Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

OBJECTIVE: Lactate accumulation is an important factor in the intervertebral disc degeneration (IVDD). Currently, the effect and underlying mechanism of action of lactate on nucleus pulposus (NP) cell inflammation during IVDD are unclear. Previous studies have found that the NLRP3 inflammasome plays...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Prolif
Auteurs principaux: Zhao, Kangcheng, An, Ran, Xiang, Qian, Li, Gaocai, Wang, Kun, Song, Yu, Liao, Zhiwei, Li, Shuai, Hua, Wenbin, Feng, Xiaobo, Wu, Xinghuo, Zhang, Yukun, Das, Abhirup, Yang, Cao
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791185/
https://ncbi.nlm.nih.gov/pubmed/33111436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12941
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires