Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Intervertebral disc degeneration (IDD) is the primary culprit of low back pain and renders heavy social burden worldwide. Pyroptosis is a newly discovered form of programmed cell death, which is also involved in nucleus pulposus (NP) cells during IDD progression. Moderate autophagy activity is criti...

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Dades bibliogràfiques
Publicat a:Oxid Med Cell Longev
Autors principals: Liao, Zhiwei, Li, Suyun, Liu, Rong, Feng, Xiaobo, Shi, Yunsong, Wang, Kun, Li, Shuai, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238599/
https://ncbi.nlm.nih.gov/pubmed/34239691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5584447
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