Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Intervertebral disc degeneration (IDD) is the primary culprit of low back pain and renders heavy social burden worldwide. Pyroptosis is a newly discovered form of programmed cell death, which is also involved in nucleus pulposus (NP) cells during IDD progression. Moderate autophagy activity is criti...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Liao, Zhiwei, Li, Suyun, Liu, Rong, Feng, Xiaobo, Shi, Yunsong, Wang, Kun, Li, Shuai, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Format: Artigo
Langue:Inglês
Publié: Hindawi 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238599/
https://ncbi.nlm.nih.gov/pubmed/34239691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5584447
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