Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Intervertebral disc degeneration (IDD) is the primary culprit of low back pain and renders heavy social burden worldwide. Pyroptosis is a newly discovered form of programmed cell death, which is also involved in nucleus pulposus (NP) cells during IDD progression. Moderate autophagy activity is criti...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Liao, Zhiwei, Li, Suyun, Liu, Rong, Feng, Xiaobo, Shi, Yunsong, Wang, Kun, Li, Shuai, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238599/
https://ncbi.nlm.nih.gov/pubmed/34239691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5584447
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