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The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction

The acid-sensing ion channel 1a (ASIC1a) is widely expressed in central and peripheral neurons where it generates transient cation currents when extracellular pH falls. ASIC1a confers pH-dependent modulation on postsynaptic dendritic spines and has critical effects in neurological diseases associate...

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Bibliografiska uppgifter
Huvudupphovsmän: Schnizler, Mikael K., Schnizler, Katrin, Zha, Xiang-ming, Hall, Duane D., Wemmie, John A., Hell, Johannes W., Welsh, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631967/
https://ncbi.nlm.nih.gov/pubmed/19028690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805110200
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