Localization and Behaviors in Null Mice Suggest that ASIC1 and ASIC2 Modulate Responses to Aversive Stimuli

Acid sensing ion channels (ASICs) generate H(+)-gated Na(+) currents that contribute to neuronal function and animal behavior. Like ASIC1, ASIC2 subunits are expressed in the brain and multimerize with ASIC1 to influence acid-evoked currents and facilitate ASIC1 localization to dendritic spines. To...

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Autores principales: Price, Margaret P., Gong, Huiyu, Parsons, Meredith G., Kundert, Jacob R., Reznikov, Leah R., Bernardinelli, Luisa, Chaloner, Kathryn, Buchanan, Gordon F., Wemmie, John A., Richerson, George B., Cassell, Martin D., Welsh, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998777/
https://ncbi.nlm.nih.gov/pubmed/24256442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12108
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