Simultaneous Disruption of Mouse ASIC1a, ASIC2 and ASIC3 Genes Enhances Cutaneous Mechanosensitivity

Three observations have suggested that acid-sensing ion channels (ASICs) might be mammalian cutaneous mechanoreceptors; they are structurally related to Caenorhabditis elegans mechanoreceptors, they are localized in specialized cutaneous mechanosensory structures, and mechanical displacement generat...

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Detalhes bibliográficos
Main Authors: Kang, Sinyoung, Jang, Jun Ho, Price, Margaret P., Gautam, Mamta, Benson, Christopher J., Gong, Huiyu, Welsh, Michael J., Brennan, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323639/
https://ncbi.nlm.nih.gov/pubmed/22506072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035225
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