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ASIC2 Subunits Target Acid-Sensing Ion Channels to the Synapse via an Association with PSD-95

Acid-sensing ion channel-1a (ASIC1a) mediates H(+)-gated current to influence normal brain physiology and impact several models of disease. Although ASIC2 subunits are widely expressed in brain and modulate ASIC1a current, their function remains poorly understood. We identified ASIC2a in dendrites,...

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Main Authors: Zha, Xiang-ming, Costa, Vivian, Harding, Anne Marie S., Reznikov, Leah, Benson, Christopher J., Welsh, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734339/
https://ncbi.nlm.nih.gov/pubmed/19571134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1284-09.2009
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