Cytotoxic Calanquinone A from Calanthe arisanensis and Its First Total Synthesis

Calanquinone A (1) was isolated from an EtOAc-soluble extract of Calanthe arisanensis through bioassay-guided fractionation. Its structure was identified by spectroscopic methods. Compound 1 showed potent cytotoxicity (EC(50) < 0.5 µg/mL) against lung (A549), prostate (PC-3 and DU145), colon (HCT...

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Main Authors: Lee, Chia-Lin, Nakagawa-Goto, Kyoko, Yu, Donglei, Liu, Yi-Nan, Bastow, Kenneth F., Morris-Natschke, Susan L., Chang, Fang-Rong, Wu, Yang-Chang, Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551759/
https://ncbi.nlm.nih.gov/pubmed/18640035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.06.099
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